Active Clinical Trials

March 7, 2024

Trial Spotlight: Helena Yu Gives an Update on the EA5182 Trial for EGFR-Mutant Non-Small Cell Lung Cancer

This phase 3 randomized controlled trial is comparing first-line treatment with osimertinib plus bevacizumab versus osimertinib alone in patients with metastatic, EGFR-mutant non-small cell lung cancer
December 19, 2023

Now Enrolling: EA2222/PUMP for Patients With Colorectal Cancer That Has Spread to the Liver

This randomized phase 3 trial is testing whether second-line treatment with hepatic arterial infusion and systemic chemotherapy is more effective than systemic chemotherapy alone
October 19, 2023

Now Enrolling: Social Genomics Study EAQ211 to Examine Known Biomarkers of Elevated Health Risk in Adolescent and Young Adult Cancer Survivors

Through a series of blood tests and patient questionnaires, this prospective observational study examines how exposures to trauma and other adverse life experiences alter the activity of genes, immune cells, and subsequent health outcomes
October 19, 2023

Now Enrolling: EA2212 for Patients with Gastric and/or Gastroesophageal Junction Cancer

This randomized phase 2 study is assessing if chemotherapy plus immunotherapy is superior to immunotherapy alone for patients with operable MSI-H/dMMR gastric and/or gastroesophageal junction cancer
August 25, 2023

Now Enrolling: EA3211 for Patients with Squamous Cell Carcinoma of the Head and Neck

This phase 3 study of oligometastatic head and neck cancer is exploring whether it is more effective to add radiation therapy to standard immunotherapy in patients with stable disease after initial chemotherapy plus immunotherapy
August 25, 2023

Now Enrolling: EA7211/STRASS 2 for Patients with High-Risk Retroperitoneal Sarcoma

The ECOG-ACRIN Sarcoma Working Group has launched its first trial, an international collaboration to evaluate chemotherapy prior to surgery in patients with retroperitoneal leiomyosarcoma or dedifferentiated liposarcoma