Active Clinical Trials

November 16, 2021
Doctor patient skin exam

ASCO Highlights Practice-Changing Results in Melanoma

The phase III DREAMseq clinical trial provides strong evidence for starting treatment with combination immunotherapy then giving targeted therapy if the disease progresses in patients with BRAF V600 mutant metastatic melanoma
November 16, 2021
Young patient and doctor with laptop

Now Enrolling: EAQ202 to Improve Adolescent and Young Adult Self-Reported Data

This pilot study is determining the feasibility and acceptability for adult and young adult participants patients between the ages of 18 and 39 in ECOG-ACRIN treatment trials to use the National Institutes of Health’s Patient-Reported Outcomes Measurement Information System (PROMIS®)
November 16, 2021
Doctor conducing skin exam

Trial Spotlight: Ravi Amaravadi on the EA6191/BAMM2 Trial for Melanoma

This phase II randomized controlled trial is evaluating the effect of adding hydroxychloroquine to treatment with dabrafenib and trametinib in patients with advanced BRAF mutant melanoma
October 19, 2021
Man on couch on laptop

Trial Spotlight: Elyse Park on EAQ171CD – the Smoke-Free Support Study 2.0

This phase II randomized controlled trial is comparing the effectiveness of two different approaches to help recently diagnosed patients with cancer become smoke-free
September 30, 2021

Now Enrolling: Phase II of EA9152 for Acute Lymphoblastic Leukemia

This phase Ib/II study is testing the effects and safety of venetoclax in combination with liposomal vincristinein patients with B-ALL or T-ALL
September 30, 2021

NCI-MATCH Eliminates the Need for a Formal Referral Letter from the Laboratories

Removing one of several steps will help speed the process for identifying patients who may be eligible to enroll for treatment in NCI-MATCH
September 30, 2021
Patient and doctor talking

Trial Spotlight: Selina Luger on the PrE0905 Study for FLT3 Mutated Acute Myeloid Leukemia

This phase II trial is exploring the targeted cancer therapy gilteritinib, a tyrosine kinase inhibitor that kills leukemia cells by binding to the mutant FLT3 protein and blocking its activity
August 17, 2021
Green tea catechin pills

Now Enrolling: EA8184 for Prostate Cancer

This phase II study is testing the effects and safety of green tea catechins (GTC) as a chemopreventive agent
August 17, 2021
Doctor talking with patient

Now Enrolling: EAA171/OPTIMUM for Myeloma

This randomized phase III trial aims to determine if the addition of ixazomib to lenalidomide improves overall survival in patients with multiple myeloma
August 17, 2021
Patient getting imaging

EA2185 Pancreatic Cyst Surveillance Study: Amendment #2 Highlights

This study is evaluating two different screening strategies for non-cancerous pancreatic cysts; recently activated amendment #2 expands the eligibility criteria
August 17, 2021
Doctor examining patient's neck

Trial Spotlight: Dan Zandberg on the EA3191 Study for Head and Neck Squamous Cell Carcinoma

This phase II trial is comparing adjuvant treatment with either reirradiation plus pembrolizumab, pembrolizumab monotherapy, or reirradiation with platinum chemotherapy
July 7, 2021
Woman on smartphone

Mi Guía (My Guide) App for Hispanic/Latina Patients with Breast Cancer

Could a culturally-sensitive app help improve endocrine therapy medication adherence in Hispanic/Latina patients undergoing breast cancer treatment?